Key Result

At-home microneedling with a 0.2 mm microneedling device produced visible skin improvements:

• 84% of participants reported their skin felt smoother.
• 82% reported improvements in skin radiance.
• 74% noticed reduced fine lines.

About the Study

This randomized, evaluator-blinded trial investigated the safety and efficacy of at-home microneedling for facial rejuvenation. Participants self-administered treatments using a 0.2 mm needle depth dermaroller (shallower than the Erra Skin Micro Infusion Device at 0.5 mm). Improvements were assessed with validated grading scales, participant self-reports, and blinded evaluator assessments.

Why It Matters

The results confirm that even shallow, at-home microneedling can deliver significant improvements in skin texture, radiance, and fine lines. Erra Skin’s patented 0.5 mm delivery system is designed to go beyond the limitations of shallow dermarollers—helping users achieve more noticeable, professional-grade results in the comfort of their own home, with safety and ease of use at its core.

Key Result

Approximately 80–90% of participants showed improvements in skin texture and wrinkle reduction after a series of microneedling treatments, with high patient satisfaction and no major adverse effects reported.

About the Study

A clinical investigation into Percutaneous Collagen Induction Therapy (microneedling) evaluated its effectiveness for scars, wrinkles, and skin laxity. Participants underwent multiple treatment sessions, and outcomes were assessed for visible improvements in skin quality and texture.

Why It Matters

The findings confirm microneedling as a safe, effective, and minimally invasive method for rejuvenating skin and stimulating natural collagen—making it a powerful alternative to more invasive procedures.

Key Result

After five monthly microneedling sessions, participants achieved an average 45% improvement in acne scars. Investigators’ photographic review reported 50–75% improvement in the majority of patients. On patient VAS, 22 rated outcomes as “good” and 4 as “excellent.” Treatment was generally well tolerated; reported events included post-inflammatory hyperpigmentation (n=5) and tram-trek scarring (n=2).

About the Study

Prospective clinical evaluation of microneedling (dermaroller) for atrophic facial acne scars in 36 patients with Fitzpatrick IV–V skin types. Patients received five sessions at monthly intervals; outcomes were measured via blinded photographic grading (quartile scale) and a 0–10 VAS at study end. Final assessment occurred one month after the last session.

Why It Matters

Findings support microneedling as an effective, low-cost option for improving post-acne atrophic scarring in darker skin types, with little downtime and a manageable side-effect profile when performed in a clinical protocol.

Key Result

After six microneedling sessions over 12 weeks, participants showed noticeable clinical improvement in photoaged facial skin. Skin biopsies demonstrated statistically significant increases in collagen types I, III, and VII, as well as newly synthesized collagen and tropoelastin; total elastin decreased significantly.

About the Study

Prospective clinical evaluation in 10 patients with Fitzpatrick III–IV skin and Glogau class II–III wrinkles. Each participant received six microneedling treatments at 2-week intervals. Standardized photography and skin biopsies were collected at baseline, and at 1 and 3 months after starting treatment. Quantitative histology assessed epidermal thickness and levels of collagen I, III, VII, newly synthesized collagen, total elastin, and tropoelastin.

Why It Matters

The study provides objective tissue-level evidence (biopsy-proven changes in structural proteins) alongside visible improvement, supporting microneedling as a minimally invasive option for photoaged skin. Authors note that multiple sessions are usually needed to maintain improvements.

Key Result

This review identifies microneedling as a safe, minimally invasive, and effective treatment for a range of dermatologic concerns, including acne scars, other scars, wrinkles (rhytides), and striae.

About the Study

A narrative review of the medical literature on microneedling in dermatology. The authors consolidate evidence on clinical outcomes and provide a practical guide that covers pretreatment recommendations, procedural technique, and post-treatment considerations.

Why It Matters

By summarizing published data and outlining best practices, the review underscores microneedling’s role as a versatile, evidence-supported procedure in aesthetic dermatology.

Key Result

In a retrospective analysis of 480 patients treated with percutaneous collagen induction (Medical Roll-CIT), patients in the German cohort self-rated improvement at 60–80%. In 20 biopsied patients, histology at 6 months showed a considerable increase in collagen and elastin deposition; at 1 year the epidermis displayed ~40% thickening of the stratum spinosum with normal rete ridges.

About the Study

A retrospective study of 480 patients from South Africa and Germany with fine wrinkles, skin laxity, scarring, and stretch marks. Most patients had one treatment (some up to four). All were pre-treated with topical vitamins A and C for at least 4 weeks before the procedure.

Why It Matters

The authors conclude that percutaneous collagen induction is a simple and repeatable method for treating wrinkles and scars, in which the epidermis remains intact and regenerative changes in the dermis are observed.

Key Result

In 30 participants who underwent microneedling:

• 400% increase in collagen and elastin observed at 6 months post-treatment (biopsy confirmed)
• 85% of participants demonstrated significant collagen increases
• 80% of participants showed enhanced skin elasticity, improved firmness, and reduced laxity

About the Study

Clinical evaluation of microneedling in 30 individuals with varying skin concerns, including aging. Each participant received three microneedling sessions at 4-week intervals. Skin biopsies were performed before and after treatment to measure collagen levels and skin elasticity.

Why It Matters

The authors report microneedling as an effective method for skin rejuvenation, with measurable improvements in both collagen production and skin elasticity following a short treatment series.